- Student Government Association
- African American Association
- Agriculture Club
- American Dental Hygienists
- Art Club
- Basketball Club
- College Democrats
- College Republicans
- Communications Club
- Dental Students Association
- DeSoto Campus Ambassadors
- Hardee Campus Ambassadors
- Institute for Healthcare Improvement (IHI)
- Jac Pac
- Latin Student Organization
- Phi Beta Lambda
- Phi Theta Kappa
- Radiography Club
- Rotaract
- Soccer Club
- Student Nurses Association
- Student Practical Nurses
- Veterans Club of South Florida State College (VCSFSC)
- Volleyball Club
Student Nurses Association
This association promotes professionalism in nursing, provides students in Practical Nursing (PN), Associate Degree in Nursing (ADN), and Bachelor of Science in Nursing (BSN) programs with a bridge to the graduate professional organization, and introduces students to political involvement that has an impact on health care.
