- Student Government Association
- African American Association
- Agriculture Club
- American Dental Hygienists
- Art Club
- Basketball Club
- College Democrats
- College Republicans
- Communications Club
- Dental Students Association
- DeSoto Campus Ambassadors
- Hardee Campus Ambassadors
- Institute for Healthcare Improvement (IHI)
- Jac Pac
- Latin Student Organization
- Phi Beta Lambda
- Phi Theta Kappa
- Radiography Club
- Rotaract
- Soccer Club
- Student Nurses Association
- Student Practical Nurses
- Veterans Club of South Florida State College (VCSFSC)
- Volleyball Club
Agriculture Club
The club was created for those interested in the industry to be able to get out and help locally. Through this club, students are able to network within the industry so that they have a better chance of employment when they graduate. The club volunteers at local events (including non-agricultural events), networks with businesses, takes tours of local farms, and hosts fundraising events.
